The proven efficacy of 21Collagen
Our collagen-based products are backed by rigorous dermatological studies that confirm their effectiveness in improving skin elasticity, reducing wrinkles, and revitalizing the complexion. Our unique formula is clinically tested to deliver visible, long-lasting results and is suitable for all skin types.






Analysis of 21Collagen Ingredients
Ingrediente 21Collagen Marine Liquid
Marine collagen is a pure, easily assimilable source of type I collagen—the body’s most abundant collagen type. It’s extracted from cold-water fish through careful processing of skin and fish by-products, without using any harmful chemicals. The hydrolyzed collagen molecules are broken down into smaller units known as bioactive collagen peptides, which the body absorbs more readily than intact collagen molecules. Marine collagen supplies the essential amino acids needed for new collagen synthesis in the skin, joints, bones, blood vessels, muscles, and other tissues. The key amino acids are glycine, proline, and hydroxyproline. Scientifically proven benefits of taking hydrolyzed marine collagen include: Improved skin appearance — Increases skin elasticity and hydration, visibly reducing wrinkles and fine lines while stimulating natural collagen production in skin fibroblasts. Enhanced joint mobility — Provides the “building blocks” for repairing cartilage and ligaments, reducing pain, inflammation, and reliance on arthritis medications. Stronger bones — Collagen makes up over 30% of bone mass, so supplementation helps prevent bone loss and lowers the risk of osteoporosis. Accelerated wound healing — Collagen peptides promote the migration and proliferation of cells involved in tissue repair. Cardiovascular support — Collagen structures contribute to arterial elasticity, helping prevent vascular stiffening. Muscle-building support — Specific collagen amino acids play a role in muscle protein synthesis. With a consistent daily intake of 10,000 mg of marine collagen, this premium product offers a natural, effective way to slow aging while maintaining your beauty, mobility, and vitality.

Marine Collagen
Marine collagen is a pure, highly bioavailable source of type I collagen—the most abundant collagen in the body. It’s extracted from cold-water fish via careful processing of fish skin and by-products, without using harmful chemicals. The hydrolyzed collagen molecules are broken down into smaller units called bioactive collagen peptides, which the body absorbs more readily than intact collagen.
Marine collagen provides the essential amino acids required for new collagen synthesis in skin, joints, bones, blood vessels, muscles, and other tissues. The key amino acids are glycine, proline, and hydroxyproline.
Scientific studies have demonstrated multiple benefits of supplementing with hydrolyzed marine collagen:
Increases skin elasticity and hydration, visibly reducing wrinkles and fine lines while stimulating natural collagen production in skin fibroblasts.
Supplies the “building blocks” for repairing cartilage and ligaments, reducing pain, inflammation, and the need for osteoarthritis medications.
Collagen makes up over 30% of bone mass; supplementation helps prevent bone loss and lowers the risk of osteoporosis.
Collagen peptides promote the migration and proliferation of cells involved in tissue repair.
Collagen structures contribute to arterial elasticity, helping to prevent vascular stiffening.
Specific collagen amino acids play a role in muscle protein synthesis.
With a consistent daily intake of 10,000 mg of marine collagen, this premium product offers a natural and effective way to slow the aging process while maintaining beauty, mobility, and vitality.

Hyaluronic Acid
Hyaluronic acid is a natural compound found in the human body's connective tissues, such as skin, joints, and synovial fluid. It plays an essential role in hydrating and lubricating these structures.
At the skin level, hyaluronic acid acts as a molecular “sponge,” capable of absorbing and storing an amazing amount of water molecules – up to 1000 times its own weight. This allows it to give the skin a smooth, supple, and hydrated appearance.
In the dermis of the skin, hyaluronic acid creates an ideal environment for the migration and proliferation of cells involved in tissue repair. It stimulates collagen production, accelerating the healing process and reducing the appearance of wrinkles.
In joints, hyaluronic acid acts as a natural lubricant and shock absorber. It is part of the composition of synovial fluid that cushions friction between cartilage surfaces during movement. Its deficiency can lead to premature wear of cartilage.
Through its gelling and viscosity properties, hyaluronic acid provides strength and elasticity to connective tissues such as tendons and ligaments. It also regulates the migration of cells involved in the repair of these structures.
Intra-articular hyaluronic acid injections are an effective option for relieving pain and improving mobility in patients with osteoarthritis. Oral supplements can increase levels of this compound in the joints.
In the formula of this premium product, the 30 mg of hyaluronic acid significantly contributes to skin hydration, joint mobility and overall tissue repair. Together with marine collagen, it offers a dual approach to beauty and mobility.

Vitamin C
Vitamin C, or ascorbic acid, is an essential nutrient with multiple vital roles in the body. The sodium ascorbate form is a stable and well-tolerated version of this vitamin.
Here are the main benefits of vitamin C from sodium ascorbate:
Powerful antioxidant: Neutralizes free radicals and reactive oxygen species, protecting cells and essential molecules from oxidative damage. Prevents premature skin aging.
Collagen synthesis : Vitamin C is an essential cofactor for enzymes involved in collagen production. It stimulates the activity of skin fibroblasts that synthesize collagen. It also increases the absorption of dietary collagen.
Immune system : Supports leukocyte (white blood cell) function and the "trapping" action of free radicals produced in the immune defense process. Increases resistance to infections.
Iron absorption : Vitamin C increases the absorption of non-heme iron (from plant sources) by 4-5 times. Prevents iron deficiency anemia.
Cardiovascular health : Acts as an antioxidant that protects blood vessels and arteries from oxidative damage. May prevent clot formation.
Energy metabolism : It is necessary for the conversion of fat into energy through the fatty acid cycle. It also supports the production of carnitine for fat burning.
Wound healing : Stimulates collagen production and cell proliferation important for wound healing and tissue repair.
The importance of dosage:
A 90 mg dose of sodium ascorbate is sufficient to contribute to the daily requirement of vitamin C and provide the health benefits associated with this essential vitamin. It is a safe and effective dose, suitable for daily use without the risk of side effects associated with high doses of ascorbic acid.
Sodium ascorbate is an excellent form of vitamin C for those who want its benefits but have a more sensitive digestive system. It is well tolerated and can be easily integrated into most supplement regimens.

Vitamin B1
Thiamine, or vitamin B1, is an essential water-soluble vitamin with vital roles in the body. Here are the main benefits of optimal thiamine intake:
Thiamine is required for the fatty-acid oxidation cycle and the citric-acid (Krebs) cycle, through which food is converted into energy (ATP). A deficiency can lead to chronic fatigue.
It participates in the synthesis of key neurotransmitters such as acetylcholine, necessary for nerve-impulse transmission. It helps maintain the health of both the peripheral and central nervous systems.
Thiamine plays a role in brain activity, memory, concentration, and mood. Deficiencies can cause memory loss, mental confusion, and irritability.
By supporting the energy metabolism of muscle cells, it ensures proper oxygen delivery to the heart muscle, protecting against heart disease.
It’s essential for the metabolism of carbohydrates, proteins, and fats from the diet, enabling cells to use these nutrients efficiently.

Vitamin B2
Riboflavin, also known as vitamin B2, is a water-soluble vitamin essential for numerous metabolic processes in the body. Here are its main roles and benefits:
Energy metabolism – Riboflavin is a co-factor for enzymes involved in the conversion of food into energy, through the fatty acid, amino acid and carbohydrate cycles. It participates in the production of ATP, the cellular “fuel”.
Antioxidant – Active forms of riboflavin (FMN, FAD) neutralize free radicals and reactive oxygen species, protecting cells from oxidative stress. Helps prevent age-related diseases.
Eye Health – Riboflavin is concentrated in the retina, maintaining eye cell health and preventing age-related macular degeneration. Deficiency can cause photophobia and blurred vision.
Cell Growth – It is necessary for the normal multiplication and development of red blood cells, mucous membranes and skin. It supports fetal growth during pregnancy.
Iron metabolism – Facilitates the absorption and use of iron in the body, preventing iron deficiency anemia.
Skin Health – Riboflavin maintains the integrity of mucous membranes and skin barrier systems. Deficiency can lead to mouth sores, chapped lips, seborrheic dermatitis.
Detoxification – Participates in the conversion of vitamin B6 into its active form, which contributes to detoxification and elimination of byproducts.
The importance of dosage:
The 1.1 mg dose of riboflavin is in line with the daily recommendations for most adults, ensuring that basic needs are met without resorting to excessive doses, which are unnecessary given riboflavin's water solubility (the body eliminates excess through urine). This dose helps prevent deficiencies that can lead to symptoms such as cracked skin and tired eyes.
Vitamin B2 is often included in multivitamin supplements and formulas dedicated to skin and eye health, due to its beneficial effects and excellent safety profile.

Vitamin B3
Vitamin B3, also known as niacinamide, is one of the forms of niacin that does not cause redness or vasodilation, making it a preferred form in dietary supplements and skin care products. It is essential for many metabolic processes and plays an important role in skin health, the nervous system, and maintaining blood cholesterol levels.
Main benefits:
Energy production – Niacinamide is involved in the release of energy from nutrients in the form of ATP, the cellular fuel. It participates in the metabolism of carbohydrates, fats, and proteins.
Skin health – It has multiple benefits for the skin, such as: reducing clogged pores, regulating sebum production, treating hyperpigmentation, improving skin texture and firmness. It stimulates the renewal of skin layers.
Brain function – Contributes to the synthesis of neurotransmitters such as serotonin, dopamine and GABA, essential for cognitive function, mood and sleep. May improve symptoms of depression and anxiety.
Controls cholesterol levels – Niacinamide helps maintain a healthy lipid profile, reducing “bad” LDL cholesterol and triglycerides. Beneficial for cardiovascular health.
Immune system – Supports the activity of defense cells, such as lymphocytes and natural killer cells. Reduces inflammation and oxidative stress.
DNA Metabolism – It is essential for DNA repair, maintenance, and replication. It plays a role in cell division and cell reproduction.
Regulating insulin levels – In high doses, niacinamide can increase insulin sensitivity and improve insulin resistance associated with type 2 diabetes.
The importance of dosage:
The 16 mg dose of niacinamide is considered adequate to support metabolic health and provide dermatological benefits, without the risks associated with high doses of niacin (which can cause side effects such as flushing or skin redness). It is a safe and effective dose for most adults to improve overall health and skin.
Vitamin B3 in the form of niacinamide is frequently included in multivitamin supplements and cosmetic products due to its positive effects on the skin and metabolism.

Vitamin B5
Pantothenic acid, or vitamin B5, is an essential water-soluble vitamin with multiple important metabolic and physiological roles in the body:
Energy production – Part of coenzyme A, a compound involved in the release of energy from fats, proteins, and carbohydrates through the fatty acid cycle and citric acid cycle. Essential for the production of ATP.
Hormone synthesis – It is necessary for the production of steroid hormones such as cortisol, testosterone, estrogens, and progesterone in the adrenal glands and sex glands.
Cholesterol metabolism – Participates in the conversion of cholesterol into bile acids, facilitating the digestion of fats and the absorption of fat-soluble vitamins A, D, E and K.
Skin and Hair Health – Helps maintain the integrity of cell membranes in the skin and hair follicles. Deficiency can cause dermatitis, itching, hair loss.
Nervous system function – Pantothenic acid participates in the synthesis of neurotransmitters such as acetylcholine, necessary for the transmission of nerve impulses.
Red blood cell formation – Pantothenic acid is needed for the proper synthesis of hemoglobin and erythrocyte membranes.
Immune system – Plays a role in the production of antibodies and the activity of leukocytes to defend against infections.
The importance of dosage:
A 5 mg dose of vitamin B5 is sufficient to meet the daily requirement for most adults, contributing to metabolic health and general well-being. It is an adequate amount to maintain essential physiological functions without the risk of overdose.
Vitamin B5 is often included in multivitamin supplements and skin care products, being well tolerated and having an excellent safety profile at recommended doses.

Vitamin B6
Pyridoxine, or vitamin B6, is an essential water-soluble vitamin with multiple important roles in the body:
Protein metabolism – Participates in the metabolism of amino acids, the building blocks of proteins. It is essential for the efficient breakdown and use of dietary proteins.
Red blood cell production – Pyridoxine is necessary for the proper synthesis of hemoglobin, the major component of red blood cells responsible for transporting oxygen.
Neurotransmitter formation – It is involved in the production of serotonin, dopamine, GABA and noradrenaline, neurotransmitters that regulate mood, sleep and cognitive functions.
Hormonal Balance – Helps maintain optimal levels of hormones such as estrogen, progestin, and testosterone. Relieves symptoms of premenstrual syndrome.
Immune function – Pyridoxine supports lymphocyte activity and antibody production to defend against infections and autoimmune diseases.
Cardiovascular Health – Reduces homocysteine levels, a risk factor for heart disease and stroke. Maintains healthy arteries.
Energy metabolism – It is part of over 100 enzymatic reactions, including those involved in the production of energy from food.
The importance of dosage:
A 1.5 mg dose of vitamin B6 is adequate to meet the daily requirement of most adults, ensuring that needs for metabolic and cognitive health are met. This dose is sufficient to prevent deficiencies, which can lead to neurological symptoms and decreased immunity.
Vitamin B6 in the form of pyridoxine hydrochloride is well tolerated, and doses are generally safe when used within the recommended range. However, excessive doses can cause neuropathy, so it is important not to exceed the recommended daily dose.

Vitamin B7
Biotin, or vitamin B7, is a water-soluble vitamin with essential roles in the body. Here are the main benefits of optimal biotin intake:
Energy metabolism – Biotin is necessary for activating enzymes involved in the metabolism of carbohydrates, fats and proteins for the production of cellular energy (ATP).
Skin and Hair Health – Plays a key role in the synthesis of keratin, the major structural protein of skin, hair, and nails. Deficiencies can lead to hair loss, dermatitis, and brittle nails.
Cognitive function – Biotin contributes to the enzymatic activity necessary for the production of neurotransmitters that regulate sleep, mood, and memory.
Weight Control – Facilitates the conversion of carbohydrates into energy instead of being stored as fat. It also supports fat metabolism for calorie burning.
Blood sugar regulation – Participates in the production of glucokinase, an enzyme essential for metabolizing glucose and ensuring optimal blood sugar levels.
Immune system – Biotin is necessary for the normal replication of cells involved in immune defense, such as lymphocytes and stem cells.
Pregnancy and breastfeeding – An optimal intake of biotin is crucial for the healthy development of the skin, hair and nails of the fetus and infant.
The importance of dosage:
A 50 mcg dose of D-Biotin is sufficient to meet the daily requirements of most adults, preventing deficiencies that can lead to symptoms such as hair thinning, skin rashes, and neurological problems. This dose is considered safe and effective, and since biotin is water-soluble, excess is easily eliminated in the urine, reducing the risk of toxicity.
Vitamin B7 is often included in dietary supplements intended for hair and nail health, and is well tolerated when taken in recommended doses.

Vitamin B9
Folic acid, or vitamin B9, is an essential water-soluble vitamin with crucial roles in the body, especially in cellular development and nucleic acid synthesis. Here are the main benefits of optimal folic acid intake:
Blood Cell Formation – Folic acid is vital for the proper production of healthy red blood cells. A deficiency can lead to folate deficiency anemia, chronic fatigue, and paleness.
Fetal development – It is extremely important during pregnancy, when the need for folic acid increases significantly. It prevents serious neural tube defects in the fetus, such as spina bifida.
DNA and RNA Synthesis – Participates in metabolic processes involved in the synthesis, repair, and replication of nucleic acids in cells. Essential for normal cell division and growth.
Amino acid metabolism – Folic acid activates enzymes that metabolize amino acids such as homocysteine. It prevents its accumulation – a risk factor for cardiovascular disease.
Cognitive function – Adequate folic acid intake is linked to improved brain function, memory, and better concentration, including in the elderly.
Cardiovascular health – By reducing homocysteine levels, folic acid helps maintain healthy blood vessels and arteries.
Immune system – Folic acid is necessary for the normal replication of cells involved in immune defense, such as lymphocytes.
The importance of dosage:
The 400 mcg dose of folic acid is recommended for most adults and is especially important for women who are or may become pregnant, as it prevents developmental defects in the fetus. This dose is effective in preventing folic acid deficiency and its associated effects, such as anemia and fetal development problems.
Folic acid is commonly included in multivitamins and prenatal supplements and is well tolerated and considered safe at recommended doses. It is important to avoid excessively high doses, which can mask vitamin B12 deficiencies and have other side effects.

Vitamin B12
Cyanocobalamin is the stable and highly absorbed synthetic form of vitamin B12, an essential nutrient with multiple vital roles in the body:
Red blood cell formation – Vitamin B12 is necessary for the proper production of healthy red blood cells, rich in hemoglobin. A deficiency can lead to severe pernicious anemia.
Nervous system function – Provides the protective myelin sheath on nerves for efficient transmission of nerve impulses. Deficiency can cause nerve damage and symptoms such as numbness, tingling.
DNA synthesis – Participates in the production of nucleic acids DNA and RNA, the process essential for normal cell division and development.
Energy metabolism – It is necessary for the conversion of fats and proteins into usable energy through the citric acid cycle and the fatty acid cycle.
Red blood cell production – Ensures proper maturation of stem cells into functional erythrocytes, preventing megaloblastic anemias.
Hormonal balance – Helps regulate levels of melatonin and serotonin, hormones involved in sleep and mood.
Immune system – Vitamin B12 supports the proliferation of lymphocytes, key reactions in the body's defense against infections.
The importance of dosage:
A dose of 2.5 mcg of vitamin B12 is sufficient to meet the daily requirement of most adults and prevent deficiencies. This amount is adequate for maintaining essential bodily functions and is well tolerated, with no known risks of toxicity even at much higher doses.
Vitamin B12 in the form of cyanocobalamin is a common choice for supplementation due to its stability and low cost. It is important for vegetarians and vegans to supplement with vitamin B12, as dietary sources are primarily of animal origin.

Natural Antioxidants
The powerful selection of natural antioxidants (phytoextracts) helps repair skin damage and protects collagen reserves, while promoting the body's own production. The use of antioxidants in the prevention and repair of ultraviolet photodamage is already widely studied, being the most well-known and used indication. Having a very anti-inflammatory effect, they are able to reduce oxidative stress, protecting the skin from UV damage and improving collagen production. Due to its anti-inflammatory effect – antioxidants are able to protect against cartilage loss, improving joint function and reducing pain. Antioxidants also play an important functional role in the hair follicle cycle.

Zinc
Zinc gluconate is a form of zinc, an essential mineral, that is bound to gluconic acid to improve its absorption in the body. Zinc is crucial for numerous biological functions and is involved in over 300 enzymatic reactions in the human body.
Main benefits:
Immune Health: Zinc is vital for the maintenance and proper functioning of the immune system. It helps produce and activate immune cells, helping to protect the body against infection and disease.
Skin Health: Zinc is essential for tissue repair and maintaining skin health. It is used in the treatment of acne, eczema, and other skin conditions because it helps regulate sebum production and promotes wound healing.
Enzyme function: Participates in hundreds of processes in the body, including digestion and metabolism. Zinc is also important for the normal function of proteins and DNA.
Eye health: Zinc is crucial in maintaining healthy vision. It is an important component of the retina and helps protect the eyes against macular degeneration and other age-related vision problems.
The importance of dosage:
At 2 mg, this supplement provides a moderate amount of zinc, which can support the daily needs of most adults. The dosage is balanced enough to avoid the risk of zinc overdose, which can interfere with the absorption of other essential minerals, such as copper.
Zinc gluconate in this form is well tolerated by the body and effective in supporting overall health, especially the skin and immune system. It is a common and valuable ingredient in many dietary supplements for its diverse and fundamental benefits.

Copper
Copper gluconate is a form of copper bound to gluconic acid, which improves the absorption of this essential mineral in the body. Copper is involved in numerous vital processes, including the formation of hemoglobin and collagen, immune system function, iron absorption, and the maintenance of neurological health and hair and skin pigmentation.
Main benefits:
Collagen formation: Copper is essential for the production of collagen and elastin, important proteins that maintain the health and elasticity of skin and blood vessels.
Enzymatic function: This mineral is a cofactor for many enzymes, including those involved in energy production and antioxidant processes, protecting cells against oxidative stress.
Neurological health: Copper is crucial for maintaining normal brain function. Its deficiency can lead to neurological problems, including an increased risk of neurodegenerative diseases.
Immune system health: Contributes to the efficient functioning of the immune system and protection against infections by supporting the activity of white blood cells.
Iron absorption: Copper helps absorb iron from the digestive tract and release it from storage sites in the body, helping to prevent anemia.
The importance of dosage:
The 0.5 mg dose is adequate to support the body's daily needs without risking the toxic effects of excessive copper intake, which can interfere with the levels of other minerals, such as iron and zinc.
Copper gluconate is a well-tolerated and effective form of copper for dietary supplementation, providing important health benefits in a controlled, safe dose. It is an essential element for maintaining metabolic balance and body function.

Acerola extract
Acerola extract is derived from the acerola fruit, also known as the Barbados cherry or the Antilles cherry. This fruit is one of the richest natural sources of vitamin C, surpassing even oranges and kiwis in terms of content of this essential nutrient.
Main benefits:
Excellent source of vitamin C: Acerola is highly valued for its high vitamin C content, which is crucial for collagen synthesis, iron absorption, and immune system support. Vitamin C is also a powerful antioxidant that helps protect against oxidative stress.
Powerful antioxidants: In addition to vitamin C, acerola contains other antioxidants, such as carotenoids and bioflavonoids, which improve skin health and help prevent chronic diseases.
Immunity support: Due to its high content of vitamin C and other antioxidants, acerola extract can strengthen the immune system and help the body fight infections.
Anti-aging benefits: The antioxidants in acerola may help reduce the visible effects of aging by protecting the skin from free radical damage and stimulating collagen production for firmer, younger-looking skin.
The importance of dosage:
A 50 mg dose of acerola extract provides a significant amount of vitamin C, helping to meet daily needs and maximize antioxidant and immunostimulatory benefits. This dose is effective and safe, integrating well into a supplement regimen aimed at improving overall health and skin.
Acerola extract is a popular additive in dietary supplements due to its rich nutrient profile and associated benefits. It is particularly appreciated in formulations aimed at improving skin health and strengthening immunity.

L-lysine
L-lysine is an essential amino acid, meaning it cannot be produced by the human body and must be obtained through diet or supplements. It is vital for many functions in the body, including protein synthesis, calcium absorption, and the production of hormones and enzymes.
Main benefits:
Supports healthy skin: L-lysine is important for the formation of collagen, an essential component of the skin’s connective tissue. This can help maintain healthy skin and speed up the wound healing process.
Herpes prevention and management: L-lysine is often used to prevent and treat herpes simplex infections because it is believed to inhibit the activity of arginine, another amino acid that promotes herpes virus replication.
Calcium Absorption: Helps absorb and maintain adequate levels of calcium in the body, which is crucial for bone and tooth health.
Immune function: L-lysine contributes to the production of antibodies, playing a role in the immune response and protecting the body against pathogens.
The importance of dosage:
At a dose of 50 mg, L-lysine in the supplement can help supplement daily intake, especially for those who cannot get enough of this substance from their diet. This is a relatively small dose, as daily requirements can vary significantly depending on age and health, but it is enough to provide support in the context of a complex supplement that also includes other amino acids or nutrients.
L-lysine is a popular component in supplements aimed at skin and immune health, and its integration into supplements can support various aspects of overall health.
Guarana extract
Guarana extract comes from the seeds of a plant native to the Amazon basin, scientifically known as Paullinia cupana. It is renowned for its high caffeine content, which is often much more concentrated than in coffee beans.
Main benefits:
Energy Boost: Guarana is popular among energy-boosting supplements due to its high caffeine content. Caffeine stimulates the central nervous system, providing an energy boost and helping to reduce physical and mental fatigue.
Metabolism support: The caffeine in guarana can help speed up metabolism, which can contribute to the calorie-burning process and weight management.
Improving cognitive performance: Guarana extract can improve cognitive functions such as memory, concentration, and alertness, thanks to the stimulating effect of caffeine.
Antioxidant properties: In addition to caffeine, guarana also contains antioxidants such as tannins and saponins, which may help combat oxidative stress and promote overall health.
The importance of dosage:
A 50 mg dose of guarana extract is effective in providing the benefits of caffeine without overdoing it, thus avoiding the side effects such as jitters or insomnia that can occur with higher doses. This amount is enough to feel a boost of energy, without the risks associated with excessive stimulant consumption.
Guarana extract is often included in supplements designed to improve energy and mental performance, and is prized for its ability to provide a quick and effective boost. However, it is important for users to monitor their individual response to caffeine and adjust the dosage according to personal needs and tolerance.
Sage Extract
Sage extract comes from the sage plant, scientifically known as Salvia officinalis. Sage is used in both cooking and traditional medicine for its antioxidant, anti-inflammatory, and antimicrobial properties. Sage extract is concentrated to provide these benefits in an easy-to-use form.
Main benefits:
Antioxidant properties: Sage contains powerful antioxidant compounds, such as rosmarinic acid and flavonoids, which help protect cells from oxidative damage.
Anti-inflammatory effects: Its active compound, rosmarinic acid, has anti-inflammatory properties, which can help reduce inflammation in the body, benefiting conditions like arthritis or asthma.
Supporting cognitive health: Studies suggest that sage may improve memory and cognitive function, possibly due to its antioxidant effects and ability to improve blood circulation to the brain.
Antimicrobial properties: Sage has been traditionally used to combat bacterial and fungal infections, due to its natural compounds that can inhibit the growth of microorganisms.
The importance of dosage:
A 10 mg dose of sage extract is considered sufficient to provide its therapeutic benefits in a comprehensive supplement without overdoing it and causing side effects. This dose may help promote cognitive health and a healthy inflammatory response.
Sage extract is often included in supplements intended for cognitive health and general health support, and has a good safety profile when used in moderate doses. It is important to follow the recommended dosage, as high doses can lead to unpleasant side effects.

Papaya Extract
Papaya extract is derived from the papaya fruit, scientifically known as Carica papaya. It is prized for its digestive enzymes, particularly papain, which helps break down proteins. In addition to its digestive benefits, papaya also has antioxidant and anti-inflammatory properties.
Main benefits:
Digestive Support: The papain enzyme in papaya facilitates the digestion of proteins, making this extract useful in relieving digestive discomfort such as bloating and indigestion.
Anti-inflammatory properties: Papaya extract contains compounds that can reduce inflammation in the body. This is helpful in managing the symptoms of chronic inflammatory conditions.
Antioxidant Benefits: Papaya is rich in vitamin C, beta-carotene, and other antioxidants that protect cells against oxidative stress and free radical-induced damage.
Improves skin health: Due to its vitamin C content and other antioxidants, papaya can help improve the appearance of the skin, promoting brighter skin and reducing signs of aging.
The importance of dosage:
A 10 mg dose of papaya extract is sufficient to provide benefits in the context of a complex supplement, contributing to digestive and antioxidant support. This dose, although small, is effective in synergy with other active ingredients in the supplement.
Papaya extract is valuable in supplement formulations for its diverse properties, being a common addition to digestive health and skin care products. It is well tolerated and can be a valuable part of a supplement regimen for overall health and well-being.
Turmeric Extract
Turmeric rhizome extract comes from the turmeric plant, scientifically known as Curcuma longa. It is well known for its content of curcumin, a bioactive compound that provides most of the health benefits of turmeric. It is widely used in traditional and modern medicine for its anti-inflammatory and antioxidant properties.
Main benefits:
Anti-inflammatory properties: Curcumin is a powerful natural anti-inflammatory that can help reduce inflammation and pain associated with various conditions, such as arthritis, colitis, and other inflammatory diseases.
Antioxidant Benefits: Turmeric is a powerful antioxidant that protects cells against damage caused by free radicals, helping to prevent chronic diseases and improve overall health.
Cognitive health support: Studies suggest that curcumin may improve cognitive function and reduce the risk of neurodegenerative diseases, such as Alzheimer's and dementia.
Cardiovascular benefits: Turmeric may improve heart health by reducing inflammation and the oxidation of LDL cholesterol, which can prevent plaque formation in the arteries.
The importance of dosage:
A 10 mg dose of turmeric extract, while it may seem small, can be effective if the extract is highly concentrated and formulated to improve the bioavailability of curcumin. In many cases, turmeric extracts are optimized with additives such as piperine, which can increase the absorption and effectiveness of curcumin in the body.
Turmeric extract is a common ingredient in dietary supplements due to its robust profile of health benefits. It is important to note that to see substantial benefits, higher doses are sometimes necessary, so it is essential to consider this in the context of total daily intake and synergy with other ingredients in the supplement.
Bearberry Extract
Bearberry (Uva ursi) extract is recognized in phytotherapy for supporting urinary tract health and for its antiseptic effect. This extract contains arbutin and other active compounds with beneficial action in combating inflammation and mild infections of the bladder and kidneys.
Main benefits:
Helps maintain urinary tract health
May reduce discomfort caused by minor urinary tract infections
It acts as an antiseptic and diuretic agent, promoting the elimination of bacteria.
The importance of dosage
To achieve the desired effects and avoid any side effects, it is essential to follow the recommended dosage. Usually, bearberry supplements are administered for short periods (one to two weeks), precisely to prevent overloading the body. It is recommended to consult a specialist before starting any cure, especially if you have other health problems or are taking medication.

Grape Seed Extract
Grape seed extract is derived from grape seeds, recognized for its high concentration of antioxidants, including oligomeric proanthocyanidins (OPCs), which are known for their powerful antioxidant and anti-inflammatory properties.
Main benefits:
Antioxidant Properties: OPCs in grape seed extract are effective in neutralizing free radicals and protecting cells from oxidative stress. This helps prevent cellular damage and reduce the risk of chronic diseases.
Cardiovascular Support: Grape seed extract may improve blood circulation and help maintain healthy blood vessels by strengthening their walls. It may also reduce high blood pressure and improve lipid profiles.
Anti-inflammatory properties: Helps reduce inflammation in the body, which can be beneficial for conditions like arthritis and other chronic inflammatory conditions.
Skin health benefits: Due to its antioxidant and anti-inflammatory properties, grape seed extract may help protect the skin from UV damage and improve skin elasticity and hydration.
The importance of dosage:
A 5 mg dose of grape seed extract is considered effective in the context of a complex supplement, providing a concentrated source of antioxidants that can contribute to overall health. Even in small amounts, it can provide significant benefits due to the high antioxidant power of OPCs.
Grape seed extract is commonly included in supplements aimed at cardiovascular health and skin health due to its robust benefit profile. It is well tolerated and can be a valuable component of a supplement regimen for overall health and longevity.

9 types of collagen
9 types of collagen with different molecular weights, which penetrate all layers of the skin, from the epidermis to the dermis. The high molecular weight is intended for the upper layer of the skin, the epidermis, while the low molecular weight is intended for the deeper layer of the skin.

1% Vitamin C
1% Stabilized Vitamin C in a safe, non-irritating and effective form easily penetrates the skin, being metabolized into ascorbic acid, which then penetrates the deeper layers of the skin. Contributes to the enhanced synthesis of collagen, to increase skin elasticity and firmness. Provides powerful antioxidant protection, helping cells fight against the harmful effects of free radicals, which lead to premature aging. Brightens the skin, giving it a healthy and radiant appearance, eliminating the dull appearance.

4.5% multipeptide complex
4.5% multipeptide complex that visibly improves the condition of the epidermis, restoring its tone, smoothness, firmness and elasticity. This complex triggers the processes of skin cell regeneration, being essential for the renewal and restoration of the cellular matrix. In addition, it stimulates the natural production of hyaluronic acid, collagen and elastin, providing a visible lifting effect.

Cranberry stem cells
Cranberry stem cells improve regeneration and protect the skin from photoaging caused by IR and UV radiation. They also provide protection against blue light, which in turn causes skin pigmentation.

UV filters
UV filters play an essential role in protecting the skin from the harmful effects of ultraviolet rays, preventing premature aging. They act as a barrier, absorbing and dispersing ultraviolet radiation, keeping the skin healthy, firm and youthful.

Aloe vera juice
Aloe vera juice actively moisturizes the skin, has antioxidant properties, reduces the negative effects of ultraviolet radiation and effectively soothes the skin.

Cranberry extract
Cranberry extract – acts as a powerful antioxidant, protects skin cells from the action of free radicals and significantly slows down skin aging. Excellently tones the skin, making it firmer and more elastic.

Licorice extract
Licorice extract – evens out facial tone, stimulates collagen production and reduces inflammation.

Marine Collagen
Fish collagen or marine collagen is the closest to the protein produced by the human body. It penetrates well into the deep layers of the skin, is easily absorbed and excellently stimulates cell regeneration.
Smoothes and softens the dermis, evens out skin texture, smoothes fine lines and reduces the appearance of expression lines, increases firmness and elasticity, provides a lifting effect.

Hyaluronic acid
Hyaluronic acid is an essential component of the human body, and its main characteristic is maintaining the hydro balance of tissues at an optimal level.
Creates a protective layer on the surface of the epidermis that retains moisture, preventing its evaporation from the cells and protecting against aggressive external factors. Intensely moisturizes and softens tissues, improving skin elasticity, density and firmness. Promotes the renewal of collagen and elastin synthesis, which slows down after the age of 25 due to a decrease in the natural production of hyaluronic acid.

Palmitoyl Tripeptide-8
Palmitoyl Tripeptide-8 is an innovative cosmetic ingredient that prevents neurodermatosis caused by chemicals, UV radiation and other irritants. Its mechanism of action involves inhibiting the production of inflammatory cells, which helps to relieve skin dryness, reduce redness and diminish the effects of inflammatory reactions. Thanks to this ingredient, cosmetics become an effective solution in combating signs of premature skin aging and skin allergies.

SymCalmin® calming complex
SymCalmin® calming complex is an intelligent neuro-calming agent dedicated to itchy skin. An innovative component that eliminates skin irritation and redness, preventing the occurrence of allergic skin reactions. This component soothes delicate and itchy skin in just 30 minutes, provides long-term relief for dry and itchy skin, reduces the symptoms of dry and itchy skin, quickly reduces redness.
Discover the transformative world of beauty and health at 21Collagen, the place where innovation meets nature to create care solutions based on Liquid Marine Collagen. Through our passion for purity and efficacy, we offer a wide range of products, including Liquid Collagen, Hydrolyzed Liquid Collagen and specialties aimed at improving joint and skin health with liquid collagen for joints and liquid collagen for skin. At the heart of our philosophy is Liquid Marine Collagen, extracted from sustainable sources and refined through advanced processes to ensure the highest quality and bioavailability. This superior form of Liquid Collagen is designed to be easily absorbed by the body, thus maximizing the benefits for skin, hair, nails and joints.
With a special focus on Hydrolyzed Liquid Collagen, we ensure that each dose brings an optimal concentration of amino acids necessary for cell regeneration and to support the natural structure of the skin. This is the secret behind elastic skin, a luminous complexion and an authentic beauty that radiates from within. It is not only the skin that benefits from the virtues of collagen; our products are also formulated to provide support to the joints, with special variants such as liquid collagen for joints, which target their health and flexibility. So whether you want to combat the signs of aging, improve the strength of your hair and nails, or provide essential support to your joints, our range of products based on Liquid Marine Collagen is the perfect choice. In addition, liquid collagen for the skin offers you a concentrated solution for hydrating and revitalizing the skin, promoting a firm complexion and visibly reducing the signs of aging. Integrating this miraculous ingredient into your daily routine can transform the way your skin maintains its youthfulness and radiance. Browsing 21Collagen.ro, you will discover not only premium products, but also a trusted partner in your journey to authentic beauty and health. Each product is carefully selected and formulated to bring the regenerative power of nature into your life. Make it a habit to embrace the power of liquid marine collagen and enjoy firmer skin, stronger hair, resilient nails and healthy joints with our help. Choose to live beautifully with 21Collagen.ro.